ʻIkepili ʻoihana waena lāʻau lapaʻau

Nā mea waena lāʻau lapaʻau
ʻO nā mea i kapa ʻia he mau mea waena lāʻau lapaʻau he mau mea maka kemika a i ʻole nā ​​​​huahana kemika e pono ai ke hoʻohana ʻia i ke kaʻina hana synthesis o nā lāʻau lapaʻau. Hiki ke hana ʻia kēia mau huahana kemika i loko o nā hale hana kemika maʻamau me ka loaʻa ʻole o kahi laikini hana lāʻau lapaʻau, a hiki ke hoʻohana ʻia i ka synthesis a me ka hana ʻana i nā lāʻau lapaʻau inā e hoʻokō nā ʻōkuhi loea i kekahi mau koi pae. ʻOiai ʻo ka synthesis o nā lāʻau lapaʻau e hāʻule pū kekahi ma lalo o ka māhele kemika, ʻoi aku ka paʻakikī o nā koi ma mua o nā huahana kemika maʻamau. Pono nā mea hana o nā lāʻau lapaʻau i hoʻopau ʻia a me nā API e ʻae i ka palapala hōʻoia GMP, ʻoiai ʻaʻole nā ​​​​mea hana o nā mea waena, no ka mea, ʻo nā mea waena wale nō ka synthesis a me ka hana ʻana i nā mea maka kemika, ʻo ia nā huahana kumu a me ka haʻahaʻa loa i ke kaulahao hana lāʻau lapaʻau, a ʻaʻole hiki ke kapa ʻia he mau lāʻau lapaʻau, no laila ʻaʻole pono lākou i ka palapala hōʻoia GMP, kahi e hoʻohaʻahaʻa ai i ka paepae komo no nā mea hana waena.

ʻOihana waena lāʻau lapaʻau
ʻO nā ʻoihana kemika e hana a hana i nā mea waena organik/inorganic a i ʻole API no nā ʻoihana lāʻau lapaʻau no ka hana ʻana i nā huahana lāʻau lapaʻau i hoʻopau ʻia ma o ka synthesis kemika a i ʻole biological e like me nā kūlana maikaʻi paʻa. Maanei ua māhele ʻia nā mea waena lāʻau lapaʻau i ʻelua mau ʻoihana liʻiliʻi ʻo CMO a me CRO.

Luna Hoʻokele Waiwai (CMO)
ʻO ka ʻAhahui Hana ʻAelike e pili ana i kahi hui hana ʻaelike, ʻo ia hoʻi ke hāʻawi aku nei ka ʻoihana lāʻau lapaʻau i ke kaʻina hana i kahi hoa. Hoʻomaka ka kaulahao ʻoihana o ka ʻoihana CMO lāʻau lapaʻau me nā mea maka lāʻau lapaʻau kūikawā. Pono nā ʻoihana ma ka ʻoihana e kiʻi i nā mea maka kemika kumu a hana iā lākou i nā mea hoʻohui lāʻau lapaʻau kūikawā, a laila hana ʻia i nā mea hoʻomaka API, nā mea waena cGMP, nā API a me nā ʻano hana. I kēia manawa, ʻo nā ʻoihana lāʻau lapaʻau multinational nui e hoʻokumu i nā pilina hoʻolālā lōʻihi me kahi helu liʻiliʻi o nā mea hoʻolako koʻikoʻi, a ʻo ke ola ʻana o nā ʻoihana ma kēia ʻoihana ua ʻike nui ʻia ma o kā lākou mau hoa.

CRO
ʻO ka Hui Noiʻi ʻAelike (Lapaʻau) e pili ana i kahi hui noiʻi ʻaelike, kahi e hoʻouna aku ai nā ʻoihana lāʻau lapaʻau i ka ʻāpana noiʻi i kahi hoa. I kēia manawa, ua hoʻokumu nui ʻia ka ʻoihana ma ka hana maʻamau, R&D maʻamau a me ka noiʻi ʻaelike lāʻau lapaʻau a me ke kūʻai aku. Me ka nānā ʻole i ke ʻano hana, inā he huahana hou ka huahana waena lāʻau lapaʻau a i ʻole, ua hoʻoholo ʻia ka hoʻokūkū koʻikoʻi o ka ʻoihana e ka ʻenehana R&D ma ke ʻano he mea mua, kahi i hōʻike ʻia i nā mea kūʻai aku a i ʻole nā ​​​​hoa o ka ʻoihana.

Kaula waiwai mākeke huahana lāʻau lapaʻau
Kiʻi
(Kiʻi mai Qilu Securities)

Kaula ʻoihana o ka ʻoihana waena lāʻau lapaʻau
Kiʻi
(Kiʻi mai ka Pūnaewele ʻIke ʻOihana Kina)

Hoʻokaʻawale ʻana o nā mea waena lāʻau lapaʻau
Hiki ke hoʻokaʻawale ʻia nā mea waena lāʻau lapaʻau i nā ʻāpana nui e like me nā kahua noi, e like me nā mea waena no nā antibiotics, nā mea waena no nā lāʻau antipyretic a me analgesic, nā mea waena no nā lāʻau ʻōnaehana cardiovascular a me nā mea waena lāʻau lapaʻau no ka anti-cancer. Nui nā ʻano o nā mea waena lāʻau lapaʻau kikoʻī, e like me imidazole, furan, nā mea waena phenolic, nā mea waena aromatic, pyrrole, pyridine, biochemical reagents, sulfur-containing, nitrogen-containing, halogen compounds, heterocyclic compounds, starch, mannitol, microcrystalline cellulose, lactose, dextrin, ethylene glycol, sugar powder, inorganic salts, ethanol intermediates, stearate, amino acids, ethanolamine, potassium salts, sodium salts a me nā mea waena ʻē aʻe, etc.
ʻIkepili o ka hoʻomohala ʻana o ka ʻoihana waena lāʻau lapaʻau ma Kina
Wahi a IMS Health Incorporated, mai 2010 a 2013, ua mālama ka mākeke lāʻau lapaʻau honua i kahi ʻano ulu mau, mai US$793.6 biliona i ka makahiki 2010 a i US$899.3 biliona i ka makahiki 2013, me ka mākeke lāʻau lapaʻau e hōʻike ana i ka ulu wikiwiki mai 2014, ma muli nui o ka mākeke US. Me ka CAGR o 6.14% mai 2010-2015, manaʻo ʻia e komo ka mākeke lāʻau lapaʻau honua i kahi pōʻaiapuni ulu lohi mai 2015-2019. Eia nō naʻe, ʻoiai ke koi nui ʻia nei nā lāʻau lapaʻau, manaʻo ʻia e ikaika loa ka ulu ʻana o ka ʻupena i ka wā e hiki mai ana, me ka mākeke honua no nā lāʻau lapaʻau e kokoke ana i US$1.22 trillion i ka makahiki 2019.
Kiʻi
(Kiʻi mai IMS Health Incorporated)
I kēia manawa, me ka hoʻoponopono hou ʻana o nā ʻoihana lāʻau lapaʻau multinational nui, ka hoʻoili ʻana o ka hana multinational a me ka hoʻomaʻemaʻe hou ʻana o ka mahele hana honua, ua lilo ʻo Kina i kumu hana waena koʻikoʻi ma ka mahele hana honua ma ka ʻoihana lāʻau lapaʻau. Ua hoʻokumu ka ʻoihana waena lāʻau lapaʻau Kina i kahi ʻōnaehana piha mai ka noiʻi a me ka hoʻomohala ʻana a hiki i ka hana ʻana a me ke kūʻai aku. Mai ka hoʻomohala ʻana o nā waena lāʻau lapaʻau ma ka honua, ua haʻahaʻa mau ka pae ʻenehana hana holoʻokoʻa o Kina, he nui nā waena lāʻau lapaʻau holomua a me nā lāʻau lapaʻau hou i kākoʻo i nā ʻoihana hana waena he liʻiliʻi, aia i ke kahua hoʻomohala o ka hoʻonui ʻana i ka hoʻonohonoho huahana a me ka hoʻonui ʻana.
Ka waiwai o ka hana o ka ʻoihana waena lāʻau lapaʻau kemika ma Kina mai 2011 a 2015
Kiʻi
(Kiʻi mai ka China Business Industry Research Institute)
I ka makahiki 2011-2015, ua ulu ka hana o nā ʻoihana lāʻau lapaʻau kemika Kina i kēlā me kēia makahiki, i ka makahiki 2013, ʻo ka hana o nā ʻoihana lāʻau lapaʻau kemika Kina he 568,300 tons, ua hoʻokuʻu ʻia aku he 65,700 tons, a ma ka makahiki 2015 ua hiki aku ka hana o nā ʻoihana lāʻau lapaʻau kemika Kina ma kahi o 676,400 tons.
2011-2015 Nā helu hana hana o ka ʻoihana lāʻau lapaʻau kemika Kina
Kiʻi
(Kiʻi mai ka China Merchant Industry Research Institute)
ʻOi aku ka nui o ka lako o nā mea waena lāʻau lapaʻau ma Kina ma mua o ke koi, a ke piʻi mālie nei ka hilinaʻi ʻana i ka hoʻokuʻu aku. Eia nō naʻe, ua kau nui ʻia nā mea hoʻokuʻu aku o Kina i nā huahana nui e like me ka huaora C, penicillin, acetaminophen, citric acid a me kona mau paʻakai a me nā esters, a pēlā aku. Hōʻike ʻia kēia mau huahana e ka nui o ka huahana, nā ʻoihana hana hou aku, ka hoʻokūkū mākeke ikaika, ke kumukūʻai huahana haʻahaʻa a me ka waiwai i hoʻohui ʻia, a ʻo kā lākou hana nui ʻana ua hoʻoulu i ke kūlana o ka lako e ʻoi aku ma mua o ke koi ma ka mākeke waena lāʻau lapaʻau kūloko. ʻO nā huahana me ka ʻike ʻenehana kiʻekiʻe e hilinaʻi nui nei i ka lawe mai.
No ka pale ʻana i nā mea waena lāʻau lapaʻau amino acid, ʻo ka hapa nui o nā ʻoihana hana kūloko he hoʻokahi ʻano huahana a me ka maikaʻi paʻa ʻole, ʻo ia hoʻi no nā ʻoihana biopharmaceutical haole e hoʻopilikino i ka hana ʻana o nā huahana. ʻO kekahi mau ʻoihana wale nō me ka ikaika noiʻi a me ka hoʻomohala ikaika, nā hale hana holomua a me ka ʻike i ka hana nui hiki ke loaʻa ka loaʻa kālā kiʻekiʻe i ka hoʻokūkū.
Ka nānā ʻana i ka ʻoihana waena lāʻau lapaʻau o Kina

1, kaʻina hana hana maʻamau o ka ʻoihana lāʻau lapaʻau waena
ʻO ka mea mua, e komo i ka noiʻi a me ka hoʻomohala ʻana o ka mea kūʻai aku i nā lāʻau lapaʻau hou, kahi e koi ai i ke kikowaena R&D o ka hui i kahi hiki ke hana hou.
ʻO ka lua, i ka hoʻonui ʻana o ka huahana pilot o ka mea kūʻai aku, e hoʻokō i ke ala hana o ka hana nui, e koi ana i ka hiki ke hoʻonui ʻenekinia o ka hui i ka huahana a me ka hiki ke hoʻomaikaʻi mau i ke kaʻina hana o ka ʻenehana huahana i hana ʻia ma kahi pae ma hope, i mea e hoʻokō ai i nā pono o ka hana ʻana o ka huahana, e hoʻemi mau i ke kumukūʻai hana a hoʻonui i ka hoʻokūkū o ka huahana.
ʻO ke kolu, ʻo ia ka hoʻoheheʻe ʻana a me ka hoʻomaikaʻi ʻana i ke kaʻina hana o nā huahana i ke kahua o ka hana nui ʻana o nā mea kūʻai aku, i mea e hoʻokō ai i nā kūlana maikaʻi o nā ʻoihana haole.

2. Nā ʻano o ka ʻoihana waena lāʻau lapaʻau o Kina
ʻO ka hana ʻana o nā lāʻau lapaʻau e koi ana i ka nui o nā kemika kūikawā, ʻo ka hapa nui o ia mau mea i hana mua ʻia e ka ʻoihana lāʻau lapaʻau ponoʻī, akā me ka hohonu o ka mahele ʻana o ka hana a me ka holomua o ka ʻenehana hana, ua hoʻoili ka ʻoihana lāʻau lapaʻau i kekahi mau mea waena lāʻau lapaʻau i nā ʻoihana kemika no ka hana ʻana. He huahana kemika maikaʻi nā mea waena lāʻau lapaʻau, a ua lilo ka hana ʻana o nā mea waena lāʻau lapaʻau i ʻoihana nui i ka ʻoihana kemika honua. I kēia manawa, pono ka ʻoihana lāʻau lapaʻau o Kina ma kahi o 2,000 mau ʻano mea maka kemika a me nā mea waena i kēlā me kēia makahiki, me ke koi ma mua o 2.5 miliona tone. ʻOiai ʻo ka hoʻokuʻu ʻana aku o nā mea waena lāʻau lapaʻau ʻaʻole like me ka hoʻokuʻu ʻana aku o nā lāʻau lapaʻau e pili ana i nā kapu like ʻole ma nā ʻāina lawe mai, a me ka hana honua o nā mea waena lāʻau lapaʻau i nā ʻāina e ulu ana, ʻo nā pono hana lāʻau lapaʻau Kina o kēia manawa o nā mea maka kemika a me nā mea waena hiki ke hoʻohālikelike, he hapa liʻiliʻi wale nō o ka pono e lawe mai. A ma muli o nā kumuwaiwai nui o Kina, ua haʻahaʻa nā kumukūʻai mea maka, ua loaʻa i nā mea waena lāʻau lapaʻau he nui ka nui o nā mea i hoʻokuʻu aku.

I kēia manawa, pono ʻo Kina i nā mea maka kemika e kākoʻo ana i nā mea maka a me nā mea waena o nā ʻano he 2500 a ʻoi aku, a ua hōʻea ke koi makahiki i 11.35 miliona tone. Ma hope o 30 mau makahiki o ka hoʻomohala ʻana, ua hiki ke hoʻohālikelike ʻia nā pono hana lāʻau lapaʻau o Kina no nā mea maka kemika a me nā mea waena. ʻO ka hana ʻana o nā mea waena ma Kina, ʻo ia ka mea nui i nā lāʻau antibacterial a me antipyretic.

Ma loko o ka ʻoihana, ʻeono mau ʻano o ka ʻoihana waena lāʻau lapaʻau Kina: ʻO ka mea mua, ʻo ka hapa nui o nā ʻoihana he mau ʻoihana pilikino, hana maʻalahi, ʻaʻole nui ka unahi hoʻopukapuka kālā, ma waena o miliona a hoʻokahi a ʻelua paha tausani miliona yuan; ʻO ka lua, ua paʻa pono ka hoʻolaha ʻāina o nā ʻoihana, ʻoi aku hoʻi ma Taizhou, Zhejiang Province a me Jintan, Jiangsu Province ma ke kikowaena; ʻO ke kolu, me ka hoʻonui ʻana o ka nānā ʻana o ka ʻāina i ka palekana o ke kaiapuni, ke piʻi nei ke kaomi ma luna o nā ʻoihana e kūkulu i nā hale mālama palekana o ke kaiapuni. ʻO ka hā, wikiwiki ka wikiwiki o ka hoʻohou ʻana o ka huahana, a e hāʻule nui ka waiwai ma hope o 3 a 5 mau makahiki ma ka mākeke, e koi ana i nā ʻoihana e hoʻomohala i nā huahana hou a hoʻomaikaʻi mau i ke kaʻina hana i mea e loaʻa ai nā loaʻa kālā kiʻekiʻe. ʻO ka lima, ʻoiai ʻoi aku ka nui o ka loaʻa kālā o nā mea hana lāʻau lapaʻau ma mua o nā huahana kemika maʻamau, a ʻo ke kaʻina hana like ia, ʻoi aku ka nui o nā ʻoihana kemika liʻiliʻi e hui pū me nā kūlana o ka hana ʻana i nā mea hana lāʻau lapaʻau, e hopena ana i ka hoʻokūkū ikaika i ka ʻoihana ʻEono, i hoʻohālikelike ʻia me ka API, haʻahaʻa ka palena waiwai o ka hana ʻana i nā mea hana, a like ke kaʻina hana o ka API a me nā mea hana lāʻau lapaʻau, no laila ʻaʻole hana wale kekahi mau ʻoihana i nā mea hana, akā hoʻohana pū i ko lākou pono ponoʻī e hoʻomaka i ka hana ʻana i ka API. Ua kuhikuhi nā loea he ʻano hiki ʻole ke pale ʻia ka hana ʻana o nā mea hana lāʻau lapaʻau i ke kuhikuhi o ka hoʻomohala ʻana o ka API. Eia naʻe, ma muli o ka hoʻohana hoʻokahi ʻana o ka API, he hopena nui nā ʻoihana lāʻau lapaʻau, hoʻomohala pinepine nā ʻoihana kūloko i nā huahana akā ʻaʻohe mea hoʻohana o ka hanana. No laila, pono nā mea hana e hoʻokumu i kahi pilina lako paʻa lōʻihi me nā ʻoihana lāʻau lapaʻau, i mea e hōʻoia ai i ke kūʻai aku ʻana i nā huahana.

3, nā pale komo ʻoihana
①Nā pale o ka mea kūʻai aku
Ua hoʻomalu ʻia ka ʻoihana lāʻau lapaʻau e kekahi mau ʻoihana lāʻau lapaʻau multinational. Akahele loa nā oligarchs lāʻau lapaʻau i kā lākou koho ʻana i nā mea lawelawe outsourcing a he manawa lōʻihi ko lākou no nā mea hoʻolako hou. Pono nā ʻoihana CMO lāʻau lapaʻau e hoʻokō i nā ʻano kamaʻilio o nā mea kūʻai aku like ʻole, a pono e hele i kahi manawa lōʻihi o ka loiloi mau ma mua o ka loaʻa ʻana o ka hilinaʻi o nā mea kūʻai aku ma hope, a laila lilo i kā lākou mea hoʻolako koʻikoʻi.
②Nā pale loea
ʻO ka hiki ke hāʻawi i nā lawelawe waiwai i hoʻohui ʻia i ka ʻenehana kiʻekiʻe ke kihi o kahi ʻoihana lawelawe outsourcing lāʻau lapaʻau. Pono nā ʻoihana CMO lāʻau lapaʻau e uhaʻi i nā bottlenecks loea a i ʻole nā ​​​​​​mea ālai i kā lākou mau ala mua a hāʻawi i nā ala hoʻomaikaʻi kaʻina hana lāʻau lapaʻau e hōʻemi pono i nā kumukūʻai hana lāʻau. Me ka ʻole o ka hoʻopukapuka kālā lōʻihi a kiʻekiʻe i ka noiʻi a me ka hoʻomohala ʻana a me nā waihona ʻenehana, he paʻakikī i nā ʻoihana ma waho o ka ʻoihana ke komo maoli i ka ʻoihana.
③Nā pale talena
He mea paʻakikī i nā ʻoihana CMO ke kūkulu i kahi hui R&D a me ka hana hoʻokūkū i loko o kahi manawa pōkole e hoʻokumu i kahi kumu hoʻohālike ʻoihana cGMP-compliant.
④Nā pale hoʻoponopono maikaʻi
Ua lilo ka FDA a me nā keʻena hoʻoponopono lāʻau lapaʻau ʻē aʻe i mea koʻikoʻi i kā lākou mau koi kaohi maikaʻi, a ʻo nā huahana i hala ʻole i ka loiloi ʻaʻole hiki ke komo i nā mākeke o nā ʻāina e lawe mai ana.
⑤ Nā pale hoʻoponopono kaiapuni
ʻO nā ʻoihana lāʻau lapaʻau me nā kaʻina hana kahiko e uku i nā kumukūʻai kaohi haumia kiʻekiʻe a me ke kaomi hoʻoponopono, a ʻo nā ʻoihana lāʻau lapaʻau kuʻuna e hana nui ana i ka haumia kiʻekiʻe, ka hoʻohana ʻana i ka ikehu kiʻekiʻe a me nā huahana waiwai haʻahaʻa (e like me ka penicillin, nā huaora, a me nā mea ʻē aʻe) e alo i ka hoʻopau wikiwiki ʻana. ʻO ka pili ʻana i ka hana hou a me ka hoʻomohala ʻana i ka ʻenehana lāʻau lapaʻau ʻōmaʻomaʻo ua lilo ia i kuhikuhi hoʻomohala e hiki mai ana o ka ʻoihana CMO lāʻau lapaʻau.

4. Nā ʻoihana i helu ʻia no nā mea lapaʻau kūloko
Mai ke kūlana o ke kaulahao ʻoihana, ʻo nā ʻoihana 6 i helu ʻia o nā kemika maikaʻi e hana ana i nā mea lapaʻau waena aia ma ka hopena haʻahaʻa o ke kaulahao ʻoihana. Inā paha i ka mea lawelawe outsourcing ʻoihana a i ʻole i ka API a me ka hoʻonui ʻana i ka formulation, ʻo ka ikaika loea ke kumu hoʻoikaika mau.
Ma ke ʻano o ka ikaika ʻenehana, makemake ʻia nā ʻoihana me ka ʻenehana ma ka pae honua alakaʻi, ka ikaika mālama waiwai ikaika a me ka hoʻopukapuka nui ʻana ma R&D.
Hui I: ʻEnehana Lianhua a me Arbonne Chemical. ʻEwalu mau ʻenehana koʻikoʻi ko Lianhua Technology e like me ka ammonia oxidation a me ka fluorination ma ke ʻano he kikowaena ʻenehana, nona ka hydrogen oxidation ma ka pae alakaʻi honua. He alakaʻi honua ʻo Abenomics i nā lāʻau chiral, ʻoi aku hoʻi i kāna mau ʻenehana hoʻokaʻawale kemika a me ka racemization, a loaʻa iā ia ka hoʻopukapuka R&D kiʻekiʻe loa, e helu ana i 6.4% o ka loaʻa kālā.
Pūʻulu II: ʻEnehana Wanchang a me ʻEnehana Yongtai. ʻO ke ʻano hana hydrocyanic acid kinoea ʻōpala o Wanchang Technology ke kumu kūʻai haʻahaʻa loa a me ke kaʻina hana holomua loa no ka hana ʻana i nā esters prototrizoic acid. Ma ka ʻaoʻao ʻē aʻe, ua ʻike ʻia ʻo Yongtai Technology no kāna mau kemika fluorine maikaʻi.
Pūʻulu III: Tianma Fine Chemical a me Bikang (i ʻike mua ʻia ʻo Jiuzhang).
Hoʻohālikelike o ka ikaika loea o nā ʻoihana i helu ʻia
Kiʻi
Hoʻohālikelike o nā mea kūʻai aku a me nā hiʻohiʻona kūʻai aku o nā ʻoihana waena lāʻau lapaʻau i helu ʻia
Kiʻi
Hoʻohālikelike o ke koi ma hope a me ke ola o ka palapala Sila Nui o nā huahana o nā ʻoihana i helu ʻia
Nā kiʻi
Ka nānā ʻana i ka hoʻokūkū huahana o nā ʻoihana i helu ʻia
Nā kiʻi
ʻO ke ala e hoʻomaikaʻi ai i nā mea waena kemika maikaʻi
Nā kiʻi
(Nā kiʻi a me nā mea hana mai Qilu Securities)
Nā manaʻolana hoʻomohala o ka ʻoihana waena lāʻau lapaʻau o Kina
Ma ke ʻano he ʻoihana koʻikoʻi i ke kahua o ka ʻoihana kemika maikaʻi, ua lilo ka hana lāʻau lapaʻau i mea nui o ka hoʻomohala ʻana a me ka hoʻokūkū i nā makahiki he 10 i hala iho nei, me ka holomua o ka ʻepekema a me ka ʻenehana, ua hoʻomohala mau ʻia nā lāʻau lapaʻau he nui no ka pono o ke kanaka, ʻo ka synthesis o kēia mau lāʻau lapaʻau e pili ana i ka hana ʻana o nā mea waena lāʻau lapaʻau hou, kiʻekiʻe, no laila ua pale ʻia nā lāʻau lapaʻau hou e nā patent, ʻoiai ʻaʻohe pilikia o nā mea waena me lākou, no laila he mea hoʻohiki nui nā mea waena lāʻau lapaʻau hou ma ka home a ma waho. ʻO ka wahi hoʻomohala mākeke a me ka manaʻolana noi he mea hoʻohiki nui.
Nā kiʻi

I kēia manawa, ʻo ke kuhikuhi noiʻi o nā mea waena lāʻau lapaʻau e hōʻike nui ʻia ana i ka synthesis o nā pūhui heterocyclic, nā pūhui fluorine-loaʻa, nā pūhui chiral, nā pūhui biological, a pēlā aku. Aia nō kekahi ʻokoʻa ma waena o ka hoʻomohala ʻana o nā mea waena lāʻau lapaʻau a me nā koi o ka ʻoihana lāʻau lapaʻau ma Kina. ʻAʻole hiki ke hoʻonohonoho ʻia kekahi mau huahana me nā koi pae loea kiʻekiʻe no ka hana ʻana ma Kina a hilinaʻi nui i ka lawe ʻana mai, e like me ka piperazine anhydrous, propionic acid, a pēlā aku. ʻOiai hiki i kekahi mau huahana ke hoʻokō i nā koi o ka ʻoihana lāʻau lapaʻau kūloko ma ke ʻano o ka nui, akā ʻo ke kumukūʻai kiʻekiʻe a me ka maikaʻi ʻaʻole i kū i ke kūlana, kahi e hoʻopilikia ai i ka hoʻokūkū o nā huahana lāʻau lapaʻau a pono e hoʻomaikaʻi i ke kaʻina hana, e like me TMB, p-aminophenol, D-PHPG, a pēlā aku.
Ua manaʻo ʻia i loko o nā makahiki e hiki mai ana, e kālele ana ka noiʻi lāʻau lapaʻau hou o ka honua i nā ʻano lāʻau lapaʻau he 10: nā lāʻau lapaʻau hoʻomaikaʻi i ka hana o ka lolo, nā lāʻau anti-rheumatoid arthritis, nā lāʻau anti-AIDS, nā anti-hepatitis a me nā lāʻau viral ʻē aʻe, nā lāʻau hoʻohaʻahaʻa lipid, nā lāʻau anti-thrombotic, nā lāʻau anti-tumor, nā antagonists platelet-activating factor, nā glycoside cardiac stimulants, antidepressants, nā lāʻau anti-psychotic a me anti-anxiety, etc. No kēia mau lāʻau lapaʻau e hoʻomohala i kā lākou mau waena waena, ʻo ia ke kuhikuhi o ka hoʻomohala ʻana i nā waena waena lāʻau lapaʻau a he ala koʻikoʻi ia e hoʻonui ai i kahi mākeke hou.