Abstract: acetone catalyzed chloride a hana ʻia e ka solvent crystallization ma 1,1,3-trichloroacetone me ka maʻemaʻe kiʻekiʻe ʻaʻole i emi iho ma lalo o 99.0%, me ka hua o 45%o Hua'ōlelo nui: 1,1,3-trichloroacetone; synthesis;

———-. Olelo mua

1,1,3■ trichloroacetone he mea koʻikoʻi ko waena i ka hana ʻana o ka folic acid. I kēia manawa, 1,1,3.acetone trichloropacetone, lōʻihi hana pōʻai (48 hola), koho maikaʻi ʻole, haʻahaʻa hua, 1,1,3- ʻO ka trichloropacetone ma kahi o 17% wale nō, ma hope o ka lawe ʻana i ka wai, ʻo 51.9% wale nō kāna mea. pilikia.Heluhelu nui ka mea kakau i na palapala kuloko a me na aina e. Ma hope o nā hoʻokolohua he nui a me nā noiʻi, ua hoʻohui mākou i ka catalyst a me ka hoʻomalu ʻana i ka wikiwiki chlorine hou, e hōʻemi ana i ka manawa pane i 1,1,3-3 trichloropacetone i 24 mau hola, a me 1,1,3-3 trichloropacetone crystallization me ka maʻemaʻe ʻoi aku ma mua o 99% a me ka ʻoi aku ma mua o 45%.

II. Māhele hoʻokolohua

1. pane ʻana

0 0 0 0

1. II.

　　CHaCCHa+Cl:—ClCH.₂CCH.₃+Cl.₂CHCCH.₃+C1CH.₂CCH.₂C1+

1. Nā ʻanuʻu hoʻokolohua

I loko o kahi pahu ʻāʻī ʻehā me kahi condenser spherical 500ml, ua hoʻoulu ʻia kekahi nui o ka acetone a me ka catalyst i ka chlorine ma kahi mahana hopena o 10 ~ 30 W. Hoʻomaka ka manawa, hoʻōki i ka hele ʻana i ka chlorine i kekahi mau hola ma hope o ka hopena, a hoʻomau. e hoʻoulu ana no ka hola 1. Ua hoʻohuiʻia kahi mea hoʻoheheʻe kūikawā e like me ka mea i hoʻohuiʻia i ka hopena, i hoʻouluʻia no ka hola 1 i ka manawa e hoʻomaha ai i ka 10 ° C crystallization, e unuhi i ka 1,1,3-trichloroacetone.

1. 1,1,3. Hoʻoholo koho i ka maʻemaʻe trichloroacetone

Ua hoʻohana ʻia ʻo Varin 3700 gas chromatograph, QF・1 kolamu hoʻopiha a me ka mea ʻike FID e koho koho i ka loaʻa maʻemaʻe o ka huahana a me ka solution chloride.

1. Nā hopena o ke kūkākūkā
2. Ua hōʻike ʻia ka mana o ka catalyst ma ke koho chloride i ke koho ʻana o ka acetone chlorination

ʻO ka mana nui, Papa 1 ka papa inoa o nā hopena hoʻokolohua. Mai ka Papa 1, ua hoʻonui nui ʻia ka koho haʻahaʻa o 1,1,3-trichloroacetone (ma kahi o 19.1%) me ka ʻole o ka catalyst, a

　　ʻO ka mea hoʻohuihui amine catalyst ka mea maikaʻi loa, a hiki i 57.5%o. Nā kūlana hoʻāʻo: Innl acetone, 3nr) l chlorine, catalyst 0.6g, wela 1030 ° C,

manawa 18 hola. I loko o 12 hola va:3.9 Cao h;2

〜7 hola, vq:27 Cao h;7〜18 hola, VQ:3.9 a h. Papa 1. Nā hopena o ka mea hoʻoheheʻe i ka koho huahana

1. Ka hopena o ka velocity through-chlorine i ka hopena

Ua ʻike ʻia ka hoʻokolohua ʻaʻole maikaʻi ka koho ʻana o ka chlorine like ʻole, hoʻomaikaʻi nui i ka koho huahana a me ka hua.

Hōʻike ka papa 2 i kahi pūʻulu o nā ʻikepili hoʻāʻo.

Papa 2 Nā hopena o ka wikiwiki pass-chlorine i ke koho huahana

Ho'āʻo^ kūlana:]Petri kīʻaha 1 acetone, catalyst: papa hana 0.6go

Ua ʻike ka hoʻokolohua ʻo ka fluchlorine i ke kakahiaka (12 hola) a ma hope (8 24 h), ʻo ka hapa nui o ka chlorine i pakele i ka lohi o ka hopena a me ka wikiwiki (28 h). Ua hōʻike ʻia nā hopena he 1,1,3 i hana ʻoi aku ka lohi ma mua o

1,1-dichloroacetone. I ka wā o ka pane ʻana me

chloride, chloride, acetone, 1,1,4003000,

CICH2CCH3

o.

ʻo ia_II.Ua nui ka chlorination ma ka hui submethyl

ʻoi aku ka wikiwiki ma mua o ka hui methyl. No laila, ka

manaʻo ka mea kākau ʻo ka acetone chloride generation process reaction process:

Hana ʻia ka hopena me V1 1 2-5 ma ke ʻano nui.

E like me ka ʻikepili Papa 2, ʻo ke kauoha wikiwiki o kēlā me kēia ʻanuʻu

　　V2^”3^1 2 5>V4

Ma muli o ka wikiwiki o ka hopena o kēlā me kēia ʻanuʻu,

Hiki ke ʻike ʻia mai ka ʻikepili o ka Papa 3, ma muli o ka ʻokoʻa liʻiliʻi o ka paila ʻana ma waena o 1,1,3.trichloroacetone a me nā huahana, he mea paʻakikī loa ka hoʻokaʻawale ʻana i ka wai a me ka hoʻokaʻawale ʻana he ala maʻalahi. Hiki ke wehe ʻia nā huahana, paʻakikī ka maʻemaʻe

Mālama mākou i ka wikiwiki o ka chlorine i kēlā me kēia pae,

e hoʻokō i ke kumu o ka hōʻemi ʻana i ka manawa chlorine pass a me ka pale ʻana i ka koho o ka hoʻonui ʻana i ka wikiwiki o ka hopena lua e 1,1,3 trichloroacetone.

1. Hoʻomaʻemaʻe kristal hydrated E like me ka palapala, maʻamau ka

Lawe ʻia ka wai acetone chloride a hoʻomaʻemaʻe ʻia e ka wai e hoʻonui i ka ʻike o 1,1,3-trichloroacetone, a ua hoʻohana ka mea kākau i ka 1,1,3-trichloroacetone i crystallization mai nā huahana ʻē aʻe.

Hōʻike ka papa 3 i ka maʻemaʻe huahana i loaʻa i nā ʻano kaʻawale like ʻole.

Papa 3. Loaʻa ka maʻemaʻe o ka huahana mai nāʻano hoʻokaʻawale likeʻole

e hoʻomaikaʻi hou aku. Hiki i ka maʻemaʻe o ka huahana ma luna o 99%, a ʻoi aku ka kiʻekiʻe o ka hua ma nā ʻano he nui, a hiki i ka 45%o.1 Pono ke ʻano he 1,1,3-trichloroacetone maʻiʻo o K ma mua o 50% i ka chloride solutiono.

E koho i ka mea hoʻoheheʻe amine hui kūpono, e kāohi i ka pale chlorine lohi i ka wā mua a i ka hopena o 10 ~ 30 ° C, hiki ke hana i ka 1,1,3-trichloroacetone chloride, hoʻomaʻemaʻe ʻia e ka crystallization solvent kūikawā, loaʻa ka huahana crystalline me ka emi ʻole o 99.0%, me ka hua. o 45%, akā ʻo 1,1,3-trichloroacetone i loko o ka chloride solution pono e ʻoi aku ma mua o 50%o.Luna Nui o Athena

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