Kiʻekiʻe-maʻemaʻe pae o 1,1,3-trichloroacetone hoomakaukau

Abstract: acetone catalyzed chloride a hana ʻia e ka solvent crystallization ma 1,1,3-trichloroacetone me ka maʻemaʻe kiʻekiʻe ʻaʻole i emi iho ma lalo o 99.0%, me ka hua o 45%o Hua'ōlelo nui: 1,1,3-trichloroacetone; synthesis; kiʻekiʻe maʻemaʻe

----------.Olelo mua

1,1,3■ trichloroacetone he mea koʻikoʻi ko waena i ka hana ʻana i ka folic acid. ʻO ka trichloropacetone ma kahi o 17% wale nō, ma hope o ka lawe ʻana i ka wai, ʻo 51.9% wale nō kāna ʻike. pilikia.Heluhelu nui ka mea kakau i na palapala kuloko a me na aina e.Ma hope o nā hoʻokolohua he nui a me nā noiʻi, ua hoʻohui mākou i ka catalyst a me ka hoʻomalu i ka wikiwiki chlorine hou, e hōʻemi ana i ka manawa pane i 1,1,3-3 trichloropacetone i 24 mau hola, a me 1,1,3-3 trichloropacetone crystallization me ka maʻemaʻe ʻoi aku ma mua o 99% a me ka ʻoi aku ma mua o 45%.

II.Māhele hoʻokolohua

1. pane ʻana

0 0 0 0

1. II.

　　CHaCCHa+Cl:—ClCH.₂CCH.₃+Cl.₂CHCCH.₃+C1CH.₂CCH.₂C1+

1. Nā ʻanuʻu hoʻokolohua

I loko o ka pahu ʻāʻī ʻehā me ka condenser spherical 500ml, ua hoʻoulu ʻia kekahi nui o ka acetone a me ka catalyst i ka chlorine ma kahi mahana hopena o 10 ~ 30 W. Hoʻomaka ka manawa, hoʻōki i ka hele ʻana i ka chlorine i kekahi mau hola ma hope o ka hopena, a hoʻomau. e hoʻoulu ana no ka hola 1. Ua hoʻohuiʻia kahi mea hoʻoheheʻe kūikawā e like me ka mea i hoʻopiliʻia i ka hopena, i hoʻouluʻia no ka hola 1 i ka manawa e hoʻomaha ai i ka 10 ° C crystallization, e unuhi i ka 1,1,3-trichloroacetone.

1. 1,1,3. Hoʻoholo koho i ka maʻemaʻe trichloroacetone

Ua hoʻohana ʻia ʻo Varin 3700 gas chromatograph, QF・1 kolamu hoʻopiha a me ka mea ʻike FID no ka hoʻoholo ʻana i ka waiwai maʻemaʻe o ka huahana a me ka solution chloride.

1. Nā hopena o ke kūkākūkā
2. Ua hōʻike ʻia ka mana o ka catalyst ma ke koho chloride i ke koho ʻana o ka acetone chlorination

ʻO ka mana nui, Papa 1 ka papa inoa o nā hopena hoʻokolohua. Mai ka Papa 1, ua hoʻonui nui ʻia ka koho liʻiliʻi o 1,1,3-trichloroacetone (ma kahi o 19.1%) me ka ʻole o ka catalyst, a

　　ʻO ka mea hoʻohuihui amine catalyst ka mea maikaʻi loa, a hiki i 57.5%o. Nā kūlana hoʻāʻo: Innl acetone, 3nr) l chlorine, catalyst 0.6g, wela 1030 ° C,

manawa 18 hola. I loko o 12 hola va:3.9 Cao h;2

〜7 hola, vq:27 Cao h;7〜18 hola, VQ:3.9 a h. Papa 1. Nā hopena o ka catalyst ma ke koho koho huahana

1. Ka hopena o ka velocity through-chlorine i ka hopena

Ua ʻike ka hoʻokolohua he maikaʻi ʻole ke koho ʻana o ka chlorine like ʻole, hoʻomaikaʻi nui i ka koho a me ka hua.